July 12th, 2010 @ 8:00PM ET |
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| Rd | Pick | Team | Selection |
| 1 | 1 | WEY | Mike Trout (OF - LAA) |
| 1 | 2 | TIJ (from TKO) | Mike Montgomery (P - KC) |
| 1 | 3 | ARL (from TIJ) | Julio Teheran (P - Atl) |
| 1 | 4 | RAK | Tyler Matzek (P - Col) |
| 1 | 5 | RAK (from GLD) | Tanner Scheppers (P - Tex) |
| 1 | 6 | LV | Randall Delgado (P - Atl) |
| 1 | 7 | LV (from WP) | Michael Pineda (P - Sea) |
| 1 | 8 | ARL | Eric Hosmer (1B - KC) |
| 1 | 9 | TKO (from PEO) | Mike Minor (P - Atl) |
| 1 | 10 | LV (from SC) | Aroldis Chapman (P - Cin) |
| 1 | 11 | BRW | Christian Friedrich (P - Col) |
| 1 | 12 | RAK (from QC) | Jacob Turner (P - Det) |
| 2 | 1 | TKO | Jordan Lyles (P - Hou) |
| 2 | 2 | SC (from GLD) | -- |
| 2 | 3 | RAK (from TIJ) | Brett Lawrie (2B - Mil) |
| 2 | 4 | RAK | Casey Crosby (P - Det) |
| 2 | 5 | LV (from QC) | Aaron Crow (P - KC) |
| 2 | 6 | TKO (from PEO) | Zach Stewart (P - Tor) |
| 2 | 7 | WEY | -- |
| 2 | 8 | BRW | Zach Britton (P - Bal) |
| 2 | 9 | TKO (from LV) | Jiovanni Mier (SS - Hou) |
| 2 | 10 | QC (from WP) | Dustin Ackley (2B - Sea) |
| 2 | 11 | SC | -- |
| 2 | 12 | LV (from ARL) | Ryan Westmoreland (OF - Bos) |
| S | 1 | WEY | John Lamb (P - KC) |
| S | 2 | SC | Kyle Gibson (P - Min) |
| S | 3 | SC | Dee Gordon (SS - LAD) |