July 12th, 2005 @ 8:00PM ET |
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| Rd | Pick | Team | Selection |
| 1 | 1 | QC (from BIZ) | Adam Miller (P - Cle) |
| 1 | 2 | PLY | Jon Lester (P - Bos) |
| 1 | 3 | RAK | Chad Billingsley (P - LAD) |
| 1 | 4 | QC | Ian Stewart (3B - Col) |
| 1 | 5 | LV (from GLD) | Joel Guzman (SS - LAD) |
| 1 | 6 | WS | Francisco Liriano (P - Min) |
| 1 | 7 | RAK (from TIJ) | Brandon Wood (SS - LAA) |
| 1 | 8 | TKO | Jeff Niemann (P - TB) |
| 1 | 9 | WEY | Stephen Drew (SS - Ari) |
| 1 | 10 | QC (from HAV) | Jeremy Hermida (OF - Fla) |
| 1 | 11 | TKO (from LV) | Daric Barton (1B - Oak) |
| 1 | 12 | LV (from BRW) | Chris Nelson (SS - Col) |
| 2 | 1 | WS | Hanley Ramirez (SS - Bos) |
| 2 | 2 | QC | Brian Dopriak (1B - ChC) |
| 2 | 3 | QC (from HAV) | Lastings Milledge (OF - NYM) |
| 2 | 4 | TKO (from LV) | Andy LaRoche (3B - LAD) |
| 2 | 5 | TKO (from BRW) | Joel Zumaya (P - Det) |
| 2 | 6 | TKO (from TIJ) | Thomas Diamond (P - Tex) |
| 2 | 7 | PLY | Dustin Pedroia (2B - Bos) |
| 2 | 8 | WEY (from GLD) | Carlos Quentin (OF - Ari) |
| 2 | 9 | WEY | Conor Jackson (OF - Ari) |
| 2 | 10 | RAK | Yaseimero Petit (P - NYM) |
| 2 | 11 | BIZ | Eric Duncan (3B - NYY) |
| 2 | 12 | TKO | Billy Butler (OF - KC) |